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PregnancyΓÇöTretinoin has not been studied in pregnant women. Topical tretinoin is not recommended during pregnancy. Topical tretinoin has been shown to cause delayed bone development in some animal fetuses. Before using this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

Breast-feedingΓÇöIt is not known whether tretinoin passes into the breast milk. Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctors.

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ChildrenΓÇöStudies on this medicine have been done only in adult patients, and there is no specific information comparing use of this medicine in children with use in other age groups. Children are unlikely to have skin problems due to the sun. In older children treated for acne, tretinoin is not expected to cause different side effects or problems than it does in other age groups.

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Older adultsΓÇöMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of tretinoin in patients 50 years of age and older with use in other age groups.

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Other medicinesΓÇöAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.

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Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin. When you are using topical tretinoin, it is especially important that your health care professional know if you are taking any of the following:

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Your symptoms may improve after just a few days. If they do not improve within 3 weeks, call your doctor.

Avoid exposure to chicken pox and measles. This drug makes you more susceptible to these illnesses. If you are exposed to them while using flunisolide, call your doctor. Do not have a vaccination or other immunization unless your doctor tells you that you may.

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If your sputum (the matter that you cough up during an asthma attack) thickens or changes color from clear white to yellow, green, or gray, call your doctor; these changes may be signs of an infection.

Inhalation devices require regular cleaning, and some require periodic replacement. Follow the directions that come with your inhaler.

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Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

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